We identified 74 loci associated with TSH (Table 1, Supplementary Data 1 and 2, and Supplementary Fig. 1) in our meta-analysis of the HUNT study (N = 55,342), the MGI biobank (N = 10,085), and the ThyroidOmics consortium23 (up to N = 54,288). Twenty-eight of the 74 loci have not been previously reported for … See more To identify potentially causal variants at TSH loci, we conducted fine-mapping using SuSiE40, which estimates the number of causal variants and obtains … See more We performed site-directed mutagenesis studies to investigate the impact on the protein expression of TG of the two independent missense variants, both … See more To further understand the biology underlying TSH associations, we prioritized associated genes, tissues, and cell types in which TSH genes are likely to be highly … See more To explore the pleiotropic effects of the TSH loci, we examined associations of the 95 non-human leukocyte antigen (HLA) independent TSH top variants with 1283 … See more WebDetailed stratified GWAS analysis for severe COVID-19 in four European populations ... (BSI) and BSI-related mortality with thyroid-stimulating hormone (TSH) levels within the reference range in a general population. Using the HUNT2 (1995-97) we included 34,619 participants with information on TSH levels. During a median follow-up ...

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WebYour search term CTSH returns the following data from GWAS Central: Change p-value threshold -log p ≥ 0 -log p ≥ 1 -log p ≥ 2 -log p ≥ 3 -log p ≥ 4 -log p ≥ 5 -log p ≥ 6 -log p ≥ 7 … Webstudies are needed to clarify the role of TSH and TSH-associated variants in thyroid cancer. Twin studies have shown TSH levels are moderately heritable, with estimates up to … ipaws everbridge

GWAS identification of TSH4 as a candidate gene for tassel …

WebNov 3, 2024 · We extracted the association of each genetic variant for TSH and fT4 from summary data of GWAS for circulating metabolomic markers and CAD. All palindromic … WebThis green energy is able to sustain 98% of our mills’ energy needs. Methane emission from the treatment of POME is a large contributor to the total operational emissions. All TSH … http://dentapoche.unice.fr/luxpro-thermostat/does-nicola-walker-have-graves-disease open source services management software