Webb23 aug. 2024 · Croft, A. P. et al. Distinct fibroblast subsets drive inflammation and damage in arthritis. Nature 570, 246–251 (2024). This article shows that lining-layer THY1– … Webb1 jan. 2010 · Thy1 expression is induced in Thy1 (-) fibroblasts by treatment with 5-aza-2-deoxycytidine, a DNA methyltransferase inhibitor. Suppression of THY1 transcription via hypermethylation of its promoter in THY1 (-) lung fibroblasts has implications in the disease idiopathic pulmonary fibrosis (IPF).
Lack of Thy1 defines a pathogenic fraction of cardiac fibroblasts …
Webb25 juli 2024 · Because Thy-1 (CD90) marks CAFs that promote tumor cell invasion in a murine model of Kras G12D -driven lung adenocarcinoma (Kras LA1 ), here we … Webb6 apr. 2024 · In fibroblasts, THY1 was shown to inhibit SFK activation and result in increased focal adhesions and reduced wound healing capability . Yet to our knowledge, no study has been conducted to investigate the interaction between THY1 and SRC in NPC cancer development or the functional relevance of their interaction. burning up in my heart like a flame
Thy1 is a positive regulator of osteoblast differentiation and
Webb27 feb. 2024 · In lung fibroblasts, a colocalization of Thy-1 with Fas (CD95) in lipid rafts promotes lung fibroblast susceptibility to apoptosis . Zhou et al . reported that Thy-1 interacts with integrin αvβ5 on lung fibroblasts and prevents contraction-induced, integrin αvβ5–dependent, latent TGF-β1 activation and myofibroblast differentiation. WebbThymocyte differentiation antigen-1 (THY1) has been reported to have an effect on lung fibroblast proliferation and fibrogenic signaling. In this study, the mechanism of THY1 in … WebbThy-1- fibroblasts produced more IL-8 than Thy-1+ fibroblasts, and when treated with interferon-gamma (IFN-gamma) up-regulated MHC class II expression more robustly. … hamilton beach flexbrew single serve filter