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KEGG ORTHOLOGY: K12908
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WebMay 28, 2014 · Phosphonoformyl derivatives 11–14 were prepared from 15a–d by the reaction with diisopropyl phenylphosphonoformate ( 16) at elevated temperature in good yields. The obtained diisopropyl esters 18a–d were deprotected by treatment with trimethylsilyl bromide in acetonitrile at room temperature. NMR and conformational analysis Webphosphonoformate-CMP CHEBI:131759 chebi:131759: CMP-5'-phosphonoformic acid 5'-O-[{[carboxy(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]cytidine Phosphonoformyl-CMP … WebJul 27, 2024 · CMP-001 is a CpGA DNA Toll-like receptor9 agonist with the ability to activate tumor-associated plasmacytoid dendritic cells to produce interferon, which in turn induces antitumor systemic immunity. Nivolumab plus ipilimumab is an anti-PD1 regimen that has shown prior promise in advanced melanoma in the CheckMate 067 clinical trial … cu boulder personal observance day