WebApr 13, 2024 · VastDB is composed of quantitative profiles that describe the inclusion levels and functional associations of alternative splicing events detected in RNA-seq data of vertebrates and tissue types. rMATS applies a statistical method to detect differential alternative splicing events between replicate RNA-seq data. WebOct 21, 2024 · The inclusion of PE1a is a very constant phenomenon in all nonmuscle tissues, notably in Dp427m transcripts ectopically expressed in peripheral blood lymphocytes or in the brain Dp427c isoform in neuronal cells [13,33].
SURVIV for survival analysis of mRNA isoform variation
WebJun 12, 2024 · Alternative splicing allows expression of mRNA isoforms from a single gene, expanding the diversity of the proteome. Its prevalence in normal biological and disease processes warrant precise tools... WebBoth transcript isoforms from this skipping event site, i.e. in which the exon is either included (inclusion isoform) or excluded (skipping isoform), are typically present in one cell, and maintain a subtle balance that is vital to cellular function and dynamics. However, how the prevailing conditions dictate which isoform is expressed and what ... my account bc pension
Muscleblind-like 1 (Mbnl1) regulates pre-mRNA alternative …
WebJan 25, 2024 · The exon-inclusion ratio, also known as percent spliced in, is often regarded as one of the most effective measures of alternative splicing events. The existing … WebDec 5, 2014 · Ultra-deep RNA sequencing (RNA-Seq) has become a powerful approach for genome-wide analysis of pre-mRNA alternative splicing. We previously developed … WebNov 2, 2024 · AS-coupled poison exon inclusion is essential for rhythmic GE of SR proteins and has a global role in establishing temperature-dependent rhythmic GE profiles, both in mammals under circadian body temperature cycles and in plants in response to ambient temperature changes. my account bank