The 3′-untranslated region plays a crucial role in gene expression by influencing the localization, stability, export, and translation efficiency of an mRNA. It contains various sequences that are involved in gene expression, including microRNA response elements (MREs), AU-rich elements (AREs), and the poly(A) tail. In addition, the structural characteristics of the 3′-UTR as well as it… WebmiR-182 promotes tumor growth and increases chemoresistant of human anaplastic thyroid cancer by targeting tripartite motif 8 Yao Liu, Bing Zhang, Tiefeng Shi, Huadong Qin The Fourth Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, People’s Republic of China Abstract: Chemotherapy is …
Genome-Wide Polyadenylation Maps Reveal Dynamic mRNA 3
WebOct 1, 2024 · What Are 3' UTRs Doing? 3' untranslated regions (3' UTRs) of messenger RNAs (mRNAs) are best known to regulate mRNA-based processes, such as mRNA localization, mRNA stability, and translation. In addition, 3' UTRs can establish 3' UTR-mediated protein-protein interactions (PPIs), and thus can transmit genetic information e … liberty national life insurance wilmington
Functional 5′ UTR mRNA structures in eukaryotic translation regulation ...
WebTargetScanHuman considers matches to human 3' UTRs and their orthologs, as defined by UCSC whole-genome alignments. Conserved targeting has also been detected within … WebThe 3′ untranslated region (3′UTR) is an integral part of messenger RNAs (mRNAs), encompassing the sequence between the translational stop codon and the poly (A) tail. … WebJun 4, 2015 · Agilent Technologies has added the SureSelect Human All Exon V6, V6+UTR, and V6+COSMIC to its line of target-enrichment products. The new products are designed to address the limitations of exome sequencing, targeting hard-to-capture and multi-mapping regions. liberty national medical insurance