Cytoplasmic retention
WebApr 7, 2015 · First, cytoplasmic retention of YAP/TAZ, which was promoted either by high cell density or CytoD treatment, correlated with the induction of ciliogenesis. Second, depletion of YAP/TAZ caused a ... WebJan 1, 2005 · If the droplet is normally shed then its retention on sperm in the ejaculate may be associated with infertility, and there is considerable evidence that this is the case. …
Cytoplasmic retention
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WebApr 1, 2006 · Nucleo-cytoplasmic distribution of β-catenin is regulated by retention. J Cell Sci (2006) 119 (7): 1453–1463. β-catenin is the central signalling molecule of the … WebJun 20, 2000 · Retention by STAT2 may serve to regulate the activity of free p48 and/or guarantee that cytoplasmic pools of preassociated STAT2:p48 are available for rapid …
WebDec 7, 2024 · One was the intrinsic nature of cytoplasmic retention determined by GDOWN1’s CAS motif, the other was the artificial driving force for its accumulation in the … WebAug 1, 1999 · The MA domain of these viruses contains a "cytoplasmic targeting and retention signal (CTRS)" which is necessary for the intracytoplasmic assembly of virus particles. 186, 190 A single amino acid ...
WebNov 4, 2013 · Intron retention and cytoplasmic splicing are emerging forms of transcriptional regulation that add to the molecular diversity of mammalian cells. Evidence of the importance of nonnuclear transcript … WebInterestingly, we found that insulin treatment resulted in increased cytoplasmic Skp2 and nuclear p27 levels in the liver cells, suggesting that insulin-mediated Akt activation may induce...
WebWith regard to the mechanism behind nuclear DDX3 retention, we observed a correlation between cytoplasmic expression of CRM1 and nuclear DDX3 expression in colorectal cancer. This suggests that dysregulation of CRM1 is one of the mechanisms of nuclear DDX3 expression.
WebJun 6, 2014 · The results introduce a new paradigm where cytokine treatment prolongs nuclear retention simultaneous with decreasing rather than increasing the rate of nuclear import. ... It would thus appear that the C-terminal tail of STAT3α contributes to cytoplasmic retention of STAT3 in the cytoplasm under basal conditions, with S727 within it helping ... nothing nice about sugar and spiceWebOct 13, 2024 · If Pbs2 had a cytoplasmic retention or nuclear export role, then we might expect that even inactive Hog1–GFP accumulates in the nucleus in pbs2Δ strains. If Pbs2 were to enable the import of Hog1 not only by normal basal level phosphorylation but also by functioning as a carrier, then we could expect a nuclear exclusion signal of Hog1 in ... nothing nice to say quotesWebMar 1, 2013 · A cytoplasm retention signal would, in theory, not be affected by these interventions, whereas we observed nuclear accumulation of Htt in the setting of inhibition of nuclear export. Given its high degree of evolutionary conservation, beyond the four amino acid NES motif, it is highly plausible that N17 contains overlapping, but distinct ... nothing nondualityWebApr 8, 2014 · Cytoplasmic retention of a nucleocytoplasmic protein TBC1D3 by microtubule network is required for enhanced EGFR signaling. The hominoid oncogene TBC1D3 enhances epidermal growth factor receptor (EGFR) signaling and induces cell … www.ncbi.nlm.nih.gov nothing noteworthyWebFeb 15, 2024 · Our findings suggest that SET SUMOylation stimulates its cytoplasmic retention and inhibits PP2A activity, consequently leading to tau hyperphosphorylation and cognitive impairments, which provides a new insight into the AD-like tau pathology. Keywords: Alzheimer’s disease; Cognitive impairments; PP2A; SET SUMOylation; Tau … nothing notedWebThe cytoplasmic retention of the precursor molecule is controlled by a small region in its C-terminal part. We show that this region is responsible for the observed lack of DNA binding of the p50 precursor and controls the extent of … how to set up pin for hdfc debit cardWebMar 1, 2004 · Cytoplasmic retention of signal transducers prevails when cells are poised to receive an extracellular signal, and nuclear … nothing notes