WebOct 9, 2024 · By using microarray analysis and statistical methods, Franz et al. have demonstrated that circRHOBTB3 could act as a diagnostic and prognostic biomarker of clear cell renal cell carcinoma . Besides, it was reported that circFAM13B was decreased in the epithelial ovarian cancer specimens, whereas the specific regulatory mechanism … WebFor instance, EIF4A3 can induce the expression of circMMP9 and circASAP1, 51, 52 FUS can induce abnormally high expression of circRHOBTB3 and circ_002136 in tumors. 53, 54 Through analysis of the Circular RNA Interactome online database, 55 we found that EIF4A3 and FUS contain binding sites
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WebIn a first step, eight circRNAs (circATXN10, circCRIM1, circCSNK1G3, circGUCY1A2, more »... cLPP, circNEAT1, circRHOBTB3, and circSTIL) were identified as differentially expressed via a genome-wide circRNA-based microarray analysis of six PCa samples. Additional bioinformatics and literature data were applied for this selection process. WebFeb 11, 2024 · circRHOBTB3 was produced by splicing and circularization of the host gene RHOBTB3. As a Rho GTPase-family ATPase, the host gene RHOBTB3 is involved in membrane transport [ 8, 9] and proteasomal degradation [ 10] and can inhibit tumor growth by promoting the proteasomal degradation of HIF-α in renal cancer [ 11 ]. north coast business lending llc
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WebJan 13, 2024 · The circRHOBTB3 probe was incubated with streptavidin magnetic beads (Beaver, Suzhou, china) for 2 h to generate probe-coated beads, then incubated with cell lysates, followed by eluted with Trizol (Takara, japan), and qRT-PCR. for miR-654-3p pulled down, about 1 × 10 7 cells were collected, lysed, sonicated, and incubated with … WebThe Crossword Solver found 20 answers to "Heartthrob?", 5 letters crossword clue. The Crossword Solver finds answers to classic crosswords and cryptic crossword puzzles. … WebFigure Legend Snippet: CircRHOBTB3 is down-regulated in EOC. A Schematic illustration showing the circularization of RHOBTB3 exon 6 and exon 7 forming circRHOBTB3. B Relative expression of circRHOBTB3 in OC cell lines compared with IOSE-80 was measured by qRT-PCR. C The existence of circRHOBTB3 was validated by RT–PCR … north coast business lending